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. 2018 Mar 8;19(3):773. doi: 10.3390/ijms19030773

Figure 6.

Figure 6

Representation of the proposed mechanism. miR-25-3p is regulated by transcription factor AP-2α, and contributes to C2C12 metabolism by targeting Akt1. The arrow-head and “+” represent activation while the blunt-head and “−“ represent suppression.