APCs	antigen-presenting cells
CD	cluster of differentiation
CIS	cytokine-induced SH2-containing protein
CREB	cyclic AMPresponsive element binding protein
DAG	diacylglycerol
ERK	extracellular signal-regulated kinase
IFN	interferon
IL	interleukin
IP3	inositol 1,4,5-triphosphat
ITAM	immune-receptor tyrosine-based activation motif
ITIM	immuno-receptor tyrosine-based inhibitory motif
JAK	Janus kinase
Lck	lymphocyte-specific protein tyrosine kinase
MAPK	mitogen-activated protein kinase
MEK	mitogen-activated protein/extracellular signal-regulated kinase
MHC	major histocompatibility complex
NEMO	NF-κB essential modulator
NFAT	nuclear factor of activated T cells
NF-κB	nuclear factor-κB
PIP2	phosphatidylinositol-4,5-diphosphate
PI3K	phosphatidylinositol 3-kinase
PKCθ	protein kinase Cθ
PLCγ	phospholipase Cγ
PTP	protein tyrosine phosphatase
RA	rheumatoid arthritis
Ras	rat sarcoma
SOCS	suppressor of cytokine signaling
Stat	signal transducers and activators of transcription
TCR	T-cell receptor
ZAP70	ζ chain-associated 70 kDa tyrosine phosphoprotein