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Peiminine inhibits the LPS-induced inflammatory response in BV-2 cells. BV-2 cells were pretreated with peiminine (10, 25 or 50 μg/mL) for 1 h and then stimulated with LPS for 4 h. (A,B) The expression of the iNOS and COX-2 mRNAs was examined by quantitative real-time PCR (n = 3); (C–E) levels of the iNOS and COX-2 proteins were measured by Western blotting (n = 3). ### p < 0.001 compared to the sham group, * p < 0.05, ** p < 0.01 and *** p < 0.001 compared to the LPS group.
