. 2018 Mar 13;19(3):841. doi: 10.3390/ijms19030841

Table A1.

Intergroup comparison: the significance of the synergism and antagonism. Significance of differences of gene expression between assays treated with either BaP only, or with BaP + PCBs in “Time 1” and “Time 2”. The intergroup comparisons were obtained with Kruskal–Wallis test followed up by Dunn’s test. The level of significance is * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001. Genes for which there is no significant difference are indicated in italics. ns: no significant. Genes for which there is no significant difference are indicated in bold.

	Time 1
Genes	BaP vs. BaP + PCB118-1 µM	BaP vs. BaP + PCB118-5 µM	PCB118-1 µM vs. BaP + PCB118-1 µM	PCB118-5 µM vs. BaP + PCB118-5 µM
CYP1A1	*	**	**	**
PPARγ	*	*	**	**
Glut-1	ns	ns	**	**
Glut-4	ns	ns	*******	*******
Lipin-1a	*	**	**	**
Lipin-1b	ns	ns	**	**
ATGL	ns	ns	**	**
FABP-4	ns	ns	**	**
FAS	*	*	**	**
HSL	ns	*	*******	*******
SREBP	ns	ns	ns	*
TNFα	ns	ns	*	*
IL-6	ns	ns	ns	**
MCP-1	ns	ns	*******	*******
CXCL-10	**	**	**	**
*PAI-1*	ns	ns	ns	ns
Adiponectin	*	*	********	*******
Leptin	ns	ns	**	********
Genes	BaP vs. BaP + PCB153-1 µM	BaP vs. BaP + PCB153-5 µM	PCB153-1 µM vs. BaP + PCB153-1 µM	PCB153-5 µM vs. BaP + PCB153-5 µM
CYP1A1	ns	*	*	**
PPARγ	ns	ns	*******	*******
Glut-1	*	ns	**	*******
Glut-4	ns	ns	********	*******
Lipin-1a	**	**	**	**
Lipin-1b	ns	ns	*******	**
ATGL	ns	ns	*******	*******
FABP-4	ns	ns	*******	*******
FAS	*	*	*******	**
HSL	ns	ns	*******	*******
SREBP	ns	ns	ns	ns
TNFα	ns	**	*	*******
IL-6	ns	*	ns	**
MCP-1	*	ns	*******	*******
CXCL-10	*	*	**	**
*PAI-1*	ns	ns	ns	ns
Adiponectin	*	*	*******	*******
Leptin	ns	ns	********	********
	Time 2
Genes	BaP vs. BaP + PCB118-1 µM	BaP vs. BaP + PCB118-5 µM	PCB118-1 µM vs. BaP + PCB118-1 µM	PCB118-5 µM vs. BaP + PCB118-5 µM
CYP1A1	ns	*	ns	*
PPARγ	ns	*	ns	ns
*Glut-1*	ns	ns	ns	ns
Glut-4	ns	*	ns	**
Lipin-1a	ns	*	*	*
Lipin-1b	ns	*	*	*
*ATGL*	ns	ns	ns	ns
FABP-4	*	ns	ns	ns
FAS	*	ns	ns	ns
HSL	*	ns	*	ns
*SREBP*	ns	ns	ns	ns
*TNFα*	ns	ns	ns	ns
*IL-6*	ns	ns	ns	ns
*MCP-1*	ns	ns	ns	ns
CXCL-10	*	ns	*	*
PAI-1	ns	ns	ns	*
Adiponectin	*	**	ns	**
Leptin	ns	ns	*	**
Genes	BaP vs. BaP + PCB153-1 µM	BaP vs. BaP + PCB153-5 µM	PCB153-1 µM vs. BaP + PCB153-1 µM	PCB153-5 µM vs. BaP + PCB153-5 µM
CYP1A1	ns	ns	ns	*
*PPARγ*	ns	ns	ns	ns
Glut-1	ns	ns	*	*
Glut-4	*	*	**	*
Lipin-1a	ns	ns	*	*
Lipin-1b	ns	ns	*	*
*ATGL*	ns	ns	ns	ns
FABP-4	ns	ns	ns	*
FAS	ns	*	ns	*
HSL	ns	*	ns	*
*SREBP*	ns	ns	ns	ns
*TNFα*	ns	ns	ns	ns
IL-6	ns	*	ns	ns
MCP-1	*	ns	*	**
CXCL-10	*	**	*	**
PAI-1	ns	ns	**	**
Adiponectin	*	ns	**	ns
Leptin	ns	ns	**	*