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A low number of miR-21 sites are conserved among mice and humans. Targets in human livers or HCCs that precipitated miR-21 in Ago-CLIP (GSE97061) were compared to homolog gene identifiers from Ago-CLIP in mouse liver (GSE97058). Targets contained at least one binding site for miR-21 in the 5′UTR, CDS or 3′UTR (A). The number of binding sites at different locations in the mouse and human transcriptomes was compared (B).
