Table 1.
Association between miR-21 expression and components of miR-21 interactome dysregulated after anti-sense miR-21 treatment in SK-Hep-1 cells.
| Gene Name | Full Name | miR-21 Expression | |
|---|---|---|---|
| Correlation Coefficient | Adjusted p-Value | ||
| ANKRD46 | Ankyrin repeat domain 46 | −0.36509 | 5.30 × 10−12 |
| ARL1 | ADP ribosylation factor like GTPase 1 | 0.041021 | 1 |
| ARRDC3 | Arrestin-domain containing 3 | −0.21111 | 3.96 × 10−3 |
| CAMSAP2 | Calmodulin-regulated spectrin-associated protein family member 2 | Not defined * | Not defined * |
| CREB3L2 | cAMP responsive element binding protein 3 like 2 | 0.061419 | 1 |
| DDAH1 | Dimethylarginine dimethylaminohydrolase 1 | −0.340671 | 3.32 × 10−10 |
| DDX1 | DEAD-box helicase 1 | 0.090883 | 1 |
| DSTYK | Dual serine/threonine and tyrosine protein kinase | 0.237187 | 3.07 × 10−4 |
| EGLN1 | Egl-9 family hypoxia inducible factor 1 | 0.12549213 | 1 |
| GBP1 | Guanylate-binding protein 1 | −0.0315479 | 1 |
| GGCX | Gamma-glutamyl carboxylase | −0.2833242 | 1.38 × 10−6 |
| MARCKSL1 | MARCKS like 1 | 0.27395541 | 4.52 × 10−6 |
| PAG1 | Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.23283137 | 4.86 × 10−4 |
| PDZD8 | PDZ domain containing 8 | −0.0632384 | 1 |
| PLEKHA1 | Pleckstrin homology domain containing A1 | −0.2021841 | 8.88 × 10−3 |
| RMND5A | Required for meiotic nuclear division 5 homolog A | −0.5028372 | 0 |
| SLC46A3 | Solute carrier family 46 member 3 | −0.4672836 | 0 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | 0.3145013 | 1.88 × 10−8 |
| SPG20 | Spastic paraplegia 20 (Troyer syndrome) | −0.2245667 | 1.11 × 10−3 |
| TBC1D4 | TBC1 domain family member 4 | −0.0978456 | 1 |
| TGFBR2 | Transforming growth factor β receptor 2 | −0.1914894 | 0.0217 |
| THBS1 | Thrombospondin 1 | −0.1524996 | 0.391 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | −0.1720478 | 0.0994 |
| TPRG1L | Tumor protein p63 regulated 1 like | −0.336802 | 6.19 × 10−10 |
* Gene identifier could not be matched in expression data.