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Effects of hOCIF on proliferation and mOPG levels in mammary tumors cells, osteoclasts and mouse mesenchymal stem cells in vitro. Effects of hOCIF on the proliferation of CL66M2 (A), RAW 264.3 cells (B), and hMSC cells (C). hOCIF suppressed the cell proliferation of RAW 264.3 cells in a dose dependent manner. Effects of hOCIF on mOPG level in CL66M2 (D), RAW 264.3 cells (E) and hMSC cells (F). A significant increase was observed in hMSC cells. **, *** p < 0.01, p < 0.001.
