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. 2018 Mar 19;19(3):908. doi: 10.3390/ijms19030908

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Transmission electron microscopy (TEM) images showing nanoparticles (PCSNs, yellow arrows), confirming that the probes are inside the cells. Some of the silica nanoparticles are found within lysosomes.