Table 1.

Disruption of hCG (human chorionic gonadotropin) secretion by human placenta/trophoblast cells exposed to various EDCs (endocrine disrupting chemicals) at different concentrations and times.

	hCG Secretion	Reference
Atrazine	Decrease in BeWo cells at 10 pM–1 nM	[64]
	Increase in BeWo cells at of 0.1–1 mM	[64]
BPA	Decrease in BeWo cells at 30 μM	[56]
	Increase in primary trophoblast cells from human placenta term at 0.44, 1.1, 2.2, 4.4 or 8.8 µM	[58]
	Increase in placental explants from first trimester placenta at 1 or 0.5 nM	[65]
Chlorpyrifos	Increase in primary trophoblast cells from human placenta at term at 50 or 100 μM	[66]
DES	Decrease in BeWo cells at 0.1 pM, 10 nM or 0.1 µM	[64]
p-NP	Increase in BeWo cells at 0.1 pM	[64]
	Decrease in BeWo cells at 10 pM–1 nM	[64]
	Increase in placental explants from first trimester placenta at 1 nM	[53]
Resveratrol	Decrease in BeWo cells at 0.1–1 pM	[64]
p,p′-DDT/DDE	Decrease in JEG3 cells at 1, 10, 100 ng/mL, 1 µg/mL after 24 h	[67]
o,p′-DDT/DDE	Increase in JEG3 cells at 1, 10, 100 ng/mL, 1 µg/mL after 72 h	[67]