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Oxidative stress with H2O2 causes significant upregulation of inflammatory cytokines in iPSC-RPE cells. (A) Validation by qRT-PCR analyses of cytokines upregulated by oxidative stress. Fold changes against values obtained with H2O2-untreated cells are presented. (B) Quantification of IL6 protein was carried out by ELISA. (C) qRT-PCR of AMD-associated genes in H2O2 treated hiPSC-RPE cells. Fold changes against values obtained with H2O2-untreated cells are presented.
