Table 2.
Upregulated genes (≥2.0 fold) after A2E treatment.
| Symbols | Gene names | Fold changesa |
|---|---|---|
| CX3CL1 | C-X-C Motif Chemokine Ligand 1 | 2.1 |
| BMP4 | Bone Morphogenetic Protein 4 | 2.2 |
| CXCL12 | C-X-C Motif Chemokine Ligand 12 | 2.2 |
| IL11 | Interleukin 11 | 2.4 |
| IL1A | Interleukin 1 Alpha | 2.5 |
| CNTF | Ciliary Neurotrophic Factor | 2.6 |
| IL23A | Interleukin 23 Subunit Alpha | 3.0 |
| TNFRSF11B | TNF Receptor Superfamily Member 11b | 3.1 |
| CXCL5 | C-X-C Motif Chemokine Ligand 5 | 3.1 |
| CXCL16 | C-X-C Motif Chemokine ligand 16 | 3.4 |
| GPI | Glucose-6-Phosphate Isomerase | 3.8 |
| LIF | Leukemia Inhibitory Factor | 3.9 |
| TGFB2 | Transforming Growth Factor Beta 2 | 4.2 |
| IL7 | Interleukin 7 | 4.5 |
| CXCL2 | C-X-C Motif Chemokine Ligand 2 | 4.6 |
| CXCL1 | C-X-C motif chemokine ligand 1 | 5.4 |
| IL6 | Interleukin 6 | 5.6 |
| VEGFA | Vascular Endothelial Growth Factor A | 5.6 |
| CCL2 | C-C Motif Chemokine Ligand 2 | 5.7 |
| CCL20 | C-C Motif Chemokine Ligand 20 | 6.3 |
| SPP1 | Secreted Phosphoprotein 1 | 6.94 |
| IL1B | Interleukin 1 Beta | 9.8 |
| BMP2 | Bone Morphogenetic Protein 4 | 12.0 |
| CSF1 | Colony Stimulating Factor 1 | 13.5 |
| TNFSF10 | Tumor Necrosis Factor Superfamily Member 10 | 15.8 |
| CXCL8 | C-X-C Motif Chemokine Ligand 8 | 16.0 |
a
Fold changes were calculated against values from non-treated cells.