Skip to main content
. Author manuscript; available in PMC: 2018 May 6.
Published in final edited form as: Nat Struct Mol Biol. 2017 Nov 6;24(12):1057–1063. doi: 10.1038/nsmb.3499

Figure 3.

Figure 3

Efficient translation is associated with short poly(A) tails. (a) Cumulative median tail length distributions of genes that are enriched (n = 365) or depleted (n = 341) in ribosomes (at least 8 fold) over a 2 hour period25 that spans the time point used for mTAIL-seq (29 h). P-values were calculated using the Mann-Whitney U test between each category and all genes sampled. (b) Density plot comparing the bulk distribution of poly(A) tails between mRNAs and two classes of long non-coding RNAs: lincRNAs (long intervening non-coding RNAs) and antisense RNAs. Poly(A) tail measurements are available in Supplementary Data Set 1.