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. 2018 Mar 30;14(3):e1006945. doi: 10.1371/journal.ppat.1006945

Fig 9. OMVs induce delayed macrophage death.

Fig 9

BMDMs treated with PBS, N. gonorrhoeae purified OMVs and the pan-caspase inhibitor, Q-VD-PH (QVD) were analyzed by live-cell imaging every 30 minutes for 48 hours to determine (A) cell death (Draq7 positive cells), (B) mitochondrial membrane potential (ΔΨm, TMRM positive cells) and (C) caspase-3/7 activity (caspase fluorogenic substrate positive cells). Mean and standard error of the mean (SEM) are shown for three independent experiments, containing triplicate biological samples.