Fig. 4.

OPP-ID identifies a specific nascent proteome inherent in maintaining expansion of ESRE erythroid precursors. (A) Schematic for ESRE-based analysis of the nascent proteome associated with either expansion or maturation media. (B) Fold change (log2) of nascent protein abundance in expansion vs. maturation media treated ESRE cells per individual protein. Dotted line denotes log2 FC > 1. (C) Fold change analysis between expansion vs. maturation subdivided into groups of log2 FC. (D) Subclasses of identified genes up-regulated in ESRE expansion media. Genes listed in red have been previously implicated in hematopoiesis.