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. 2018 Feb 12;115(10):2329–2334. doi: 10.1073/pnas.1715368115

Table 2.

Funding years contributing to first-in-class products discovered through targeted or phenotypic methods

Metrics Drug Target only Total
Funding years
 All 12,840 184,015 196,855
 Targeted 9,170 166,970 176,140
 Phenotypic 3,670 17,045 20,715
Funding years per NME
 All, n = 87 (%) 167 (7) 2,390 (93) 2,557
 Targeted, n = 77 (%) 137 (5) 2,492 (95) 2,629
 Phenotypic, n = 10 (%) 367 (18) 1,704 (82) 2,071

Funding years associated with multiple NMEs are not unique.