Table 2.

Concentrations of VEGF and activation markers of platelets and endothelial cells measured in plasma of patients before, 24 h and 3 weeks after start of treatment with sunitinib

	Pre-Tx	24 h	3 week
VEGF in PPP (pg/ml)	101	110	218
N	17	17	9
SEM	18	23	72
vWF (μg/ml)	16.4	15.6	15.1
N	15	15	8
SEM	2.1	2.1	1.7
P-selectin (ng/ml)	120.1	154.3	92.4
N	15	15	8
SEM	13.2	32.5	10.4
Beta-TG (ng/ml)	39.1	36.8	26.9
N	15	15	8
SEM	5.2	7.4	6.3
RANTES (ng/ml)	4.3	4.1	3.2
N	15	15	8
SEM	0.6	0.8	0.7

Vascular endothelial growth factor (VEGF), platelet poor plasma (PPP), von Willebrand factor (vWF), beta-thromboglobulin (beta-TG)

N is the number of patients, SEM is the standard error of mean