. 2018 Mar 27;32(2):139–152. doi: 10.1007/s40259-018-0273-6

Table 3.

Benefit–risk estimates in other regions of the world based on one vaccinated birth cohort followed to 5 years of age

Region	Birth cohort	Event	Prevented RVGE	Caused IS	BR ratio (RVGE/IS)	Reference
Brazil	3,068,249	Hospitalizations Deaths	69,572 640	55 3	1265^a 213^a	[32]
Mexico	2,414,329	Hospitalizations Deaths	11,551 663	41 2	282^a 331^a	[32]
Australia	290,446	Hospitalizations Deaths	6528 NR	14 NR	466^a NR	[34]
USA	4,261,494	Hospitalizations Deaths	53,444 14	45 0.2	1093 71	[44]
Latin America	9,588,000	Hospitalizations Deaths	144,746 4124	172 10	841 395	[43]
England	656,457	Hospitalizations Deaths	13,276 2.86	35 0.03	375 88	[45]
Japan	1,018,400	Hospitalizations Deaths	17,925^b 6.3^b	50^b 0.017^b	350^b 366^b	[47]
France	791,183	Hospitalizations Deaths	11,132^b 7.43^b	6.86^b 0.0099^b	1624^b 743^b	This study

BR benefit–risk, IS intussusception, NR not reported, RVGE rotavirus gastroenteritis

^aCalculated using the data from the original publications

^bMedian values