Table 1.
Published reports of patients with splenic complications resulting from Babesia microti infection.
| Case [ref] | Year published | Age | Sex | Country | Co infection | Parasitemia | Splenomegaly | Rupture or infarct | ICS | Treatment (days) | Splenectomy |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 [17] | 2008 | 61 | M | NJ, USA | No | 5% | Mild | R | No | AZ+ATQ (7) | Yes |
| 2 [20] | 2008 | 56 | M | MN, USA | No | N/A | Moderate | R | No | N/A | Yes |
| 3 [21] | 2008 | 58 | M | NJ, USA | APG | 0.5% | Mild | I | No | AZ+ATQ | No |
| 4 [21] | 2008 | 75 | F | NY USA | No | N/A | Massive | I | No | AZ+ATQ QI+CLIN | No, expired |
| 5 [22] | 2011 | 54 | M | MA, USA | No | 3% | N/A | R | No | AZ+ATQ | No |
| 6 [23] | 2011 | 23 | M | CT, USA | No | 30% | N/A | R | No | CLIN+QI | No |
| 7 [24] | 2011 | 70 | M | NY, USA | No | NA | Mild | R | No | AZ+ATQ (14) | No, SA embolization |
| 8 [25] | 2011 | 70 | M | NY, USA | No | 8% | Mild | R | No | CLIN+QI AZ+ATQ (16) | No, SA embolization |
| 9 [25] | 2011 | 36 | M | NY, USA | No | 3–4% | Mild | R | No | AZ+ATQ (21) | No |
| 10 [26] | 2014 | 54 | M | CT, USA | No | N/A | Mild | R | No | AZ+ATQ (10) | No |
| 11 [28] | 2015 | 59 | F | CT, USA | No | 0.9% | Mild | R | No | CLIN+ AZ +ATQ (14) | Yes |
| 12 [27] | 2016 | 72 | M | Ecuador | No | 0.5% | Mild | I | No | ATQ+PRG N/A | No |
Ref – reference; ICS – immunocompromised state; M – male; F – female; R – rupture; I – infarct; AZ – azithromycin; QI – quinine; CLIN – clindamycin; ATQ – atovaquone; PRG – Proguanil; APG – Anaplasma phagocytophilum; SA – splenic artery; NJ – New Jersey; MN – Minnesota; MA – Massachusetts; CT – Connecticut; NY – New York; N/A – not applicable/reported.