Table 2.

Pairwise comparisons (N=6) of four groups of adjuvant periodontal treatments (largest difference in bold) included in the Guideline Project and summary estimates for the treatments + SRP versus SRP alone

	1. Systemic host modulator	2. Systemic antimicrobials	3. Topical antimicrobials	4. Lasers
	CAL difference between treatments in mm (95% confidence interval)
2. Systemic antimicrobials	0.06 (−0.28, 0.40)
3. Topical antimicrobials	−0.04 (−0.39, 0.32)	−0.10 (−0.35, 0.15)
4. Lasers	0.14 (−0.28, 0.56)	0.08 (−0.26, 0.42)	0.18 (−0.17, 0.52)
Summary estimate for treatment vs. SRP based on network meta-analysis*	0.42 (0.12, 0.72)	0.36 (0.19, 0.52)	0.45 (0.27, 0.64)	0.28 (−0.02, 0.57)

^*Guideline meta-analysis did not provide an estimate for these groupings