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Paxilline, but not IbTX, induces incontinence in rats. The number of urine spots counted from healthy Lewis rats treated with either vehicle, 20 mg/kg paxilline, or 0.5 mg/kg IbTX and then given an oral gavage of water and placed individually in a paper towel–lined cage for 1 hour. Data are the mean ± S.E.M. (n = 6 rats per group). **P < 0.01 compared with the vehicle-treated group.
