Figure 3.
Preclinical examples of theranostic NPs. (A) Copper sulfide NPs embedded in mesoporous silica and radiolabeled with 64Cu enable successful photothermal therapy (left) and PET imaging (right) of tumor xenografts. Reproduced from ref 117. Copyright 2015 American Chemical Society. (B) Iron oxide NPs (IONP) can be loaded with drugs, such as doxorubicin (Dox), and targeted to cancerous tissue using IGF1 to facilitate targeted chemotherapy and MRI. Reproduced from ref 137. Copyright 2015 American Chemical Society.