Table 3.
Margin control predictor of survival
| Negative Margin | Positive Margin | |||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | |
| Age | ||||
| < 65 | 1 [Reference] | 1 [Reference] | ||
| > 65 | 1.88 (1.51–2.32) | <0.001 | 1.66(1.26–2.18) | <0.001 |
| T Stage | ||||
| T1 | 1 [Reference] | 1 [Reference] | ||
| T2 | 1.16 (0.83–1.62) | 0.39 | 1.65 (0.96–2.84) | 0.07 |
| T3 | 1.58 (1.14–2.20) | 0.006 | 2.72 (1.69–4.36) | <0.001 |
| T4a | 2.13 (1.59–2.84) | <0.001 | 2.85 (1.87–4.35) | <0.001 |
| T4b | 3.52 (2.31–5.39) | <0.001 | 3.61 (2.18–5.95) | <0.001 |
| N stage | ||||
| N0 | 1 [Reference] | 1 [Reference] | ||
| N1–N3 | 2.47 (1.74–3.51) | <0.001 | 2.41 (1.61–3.58) | <0.001 |
| Charlson-Deyo Comorbidity Count | ||||
| 0 | 1 [Reference] | 1 [Reference] | ||
| 1 | 1.16 (0.87–1.55) | 0.31 | 1.23 (0.87–1.73) | 0.87 |
| > 2 | 1.63 (1.05–2.53) | 0.03 | 1.06 (0.62–1.80) | 0.62 |
| Therapy | ||||
| Surgery alone | 1 [Reference] | 1 [Reference] | ||
| Adj RT* | 0.80 (0.63–1.02) | 0.07 | 0.48 (0.35–0.68) | <0.001 |
| Adj CRT* | 0.93 (0.66–1.30) | 0.66 | 0.44 (0.30–0.65) | <0.001 |
*
OR- Odds Ratio; CI- Confidence Interval; Adj RT-Adjuvant Radiation Therapy; Adj CRT- Adjuvant Chemoradiation Therapy