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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Appetite. 2018 Feb 2;125:139–151. doi: 10.1016/j.appet.2018.01.027

Figure 2.

Figure 2

a) Mean intakes by weight (± SEM) as a function of weight of food served (g) for the total meal for children who had high (red – square) or low (blue- circle) BOLD signal activation in the left vmPFC in response to Large PS > Small PS (collapsed across ED). High and low activation levels were categorized based on a median split. Activation in the vmPFC interacted with weight of food served to influence the trajectory of the PSE curve (F1,41 = 5.70; P = 0.02). Children who had high activation in the left vmPFC increased intake from baseline by 32% more than children who had low activation in the vmPFC in response to Large PS > Small PS. Overall, children with high vmPFC activation followed a curvilinear trajectory while children with low vmPFC activation followed a linear trajectory. b) Location of the ROI tested based on a 5-mm sphere drawn around the Talairach coordinates (x, y, z; −9, 45, 2) on a sample brain template created in BrainVoyager Brain Tutor (version 2.8, Brain Innovation, Maastricht, The Netherlands). Images are pictured from both the coronal (top) and transverse (bottom) views. c) Mean intakes by weight (± SEM) as a function of weight of food served (g) for the total meal for children who had high (red – square) or low (blue- circle) BOLD signal activation in the left OFC in response to Large PS > Small PS (collapsed across ED). High and low activation levels were categorized based on a median split. Activation in the OFC interacted with weight of food served to influence the trajectory of the PSE curve (F1,41 = 8.5; P = 0.004). Children who had high activation in the left OFC increased intake from baseline by 14% more than children who had low activation in the vmPFC in response to Large PS > Small PS. Overall, children with high OFC activation followed a curvilinear trajectory while children with low OFC activation followed a linear trajectory. d) Location of the ROI tested based on a 5-mm sphere drawn around the Talairach coordinates (x, y, z; −32, 29, −3) on a sample brain template created in BrainVoyager Brain Tutor (version 2.8, Brain Innovation, Maastricht, The Netherlands). Images are pictured from both the coronal (top) and transverse (bottom) views.