Specificity of the DP antibody. (A) Western blot
analysis with the DP antibody. The glutathione transferase-fused
C-terminal fragment of DP expressed in E. coli (30 ng of
protein, lane 1) and homogenate (200 μg of protein) of COS cells
expressing receptor for DP (lanes 2, 5, and 6), EP2 (lane 3), or PGF
(lane 4) were subjected to SDS/PAGE and transferred to a
nitrocellulose membrane. The blot was immunostained with the DP
antibody (lanes 1–4), normal guinea pig IgG (lane 5), or preadsorbed
DP antibody (lane 6). (B) Immunofluorescence staining
with the DP antibody. Photographs indicate the native CHO cells (b) and
CHO cells stably expressing DP (a), EP2 receptor (c), or PGF receptor
(d).