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Effect of PGD2 infusion on sleep induction in WT and DP−/− mice. Vehicle (○) or PGD2 (10 and 50 pmol/min, ●) was infused for 6 h (black bars) into the lateral ventricle of the brain in WT (A and B) and DP−/− (C) mice. The values (means ± SEM, n = ≈5–6) were calculated as the amount of sleep for every 2 h. *, P < 0.05; **, P < 0.01, compared with the vehicle group.
