Table 1.
Categories and functional description of shRNA target genes.
| shRNA target | Category | Description |
|---|---|---|
| Kdm5c/Jarid1c/Smcx | Epigenetic modulator | Histone H3 lysine 4 demethylase |
| Kdm5d/Jarid1d/Smcy | Epigenetic modulator | Histone H3 lysine 4 demethylase |
| Kmt2a/Mll1 | Epigenetic modulator | Member of SET1/MLL complexes |
| Kmt2d/Mll2 | Epigenetic modulator | Member of SET1/MLL complexes |
| Kmt2e/Mll5 | Epigenetic modulator | Member of SET1/MLL complexes |
| Phf23 | Epigenetic modulator | Redear of H3K4me3/2 |
| Ctcf | Epigenetic modulator | Chromatin insulator |
| Bcorl1 | Epigenetic modulator | Component of BCOR complex (subtype of PRC1, PRC1.1) |
| Bcor | Epigenetic modulator | Component of BCOR complex (subtype of PRC1, PRC1.1) |
| Rad21 | Epigenetic modulator | Component of cohesin complex |
| Stag2/SA2 | Epigenetic modulator | Component of cohesin complex |
| Phf12 | Epigenetic modulator | Component of EMSY/KDM5A/SIN3B complex |
| Sin3b | Epigenetic modulator | Component of EMSY/KDM5A/SIN3B complex |
| Trrap | Epigenetic modulator | Component of TIP60 complex |
| Yy1 | Epigenetic modulator | Component of INO80 complex |
| Ruvbl2/Tip48 | Epigenetic modulator | Component of INO80 subfamily (INO80, TIP60, and SWR complexes) |
| Ruvbl1/Tip49 | Epigenetic modulator | Component of INO80 subfamily (INO80, TIP60, and SWR complexes) |
| Smarca5 | Epigenetic modulator | Component of ISWI complex (SWI/SNF) |
| Tet1 | Epigenetic modulator | DNA hydroxymethyltransferase |
| Tet3 | Epigenetic modulator | DNA hydroxymethyltransferase |
| Sf1 | Splicing factor | Splicing factor for spliceosome assembly |
| Sf3a1/PRP21 | Splicing factor | Splicing factor for spliceosome assembly (U2 snRNP) |
| Sf3b1 | Splicing factor | Splicing factor for spliceosome assembly (U2 snRNP) |
| U2af1 | Splicing factor | Splicing factor for spliceosome assembly |
| Zrsr2/URP | Splicing factor | Splicing factor for spliceosome assembly |