Table 2.
Comparison of laboratory data between A-AIH and C-AIH patients.
| Acute n = 32 (40.0%) |
Chronic n = 48 (60.0%) |
P | |
|---|---|---|---|
| HGB (g/L) | 116 ± 21 | 118 ± 26 | 0.687 |
| PLT (109/L) | 112 (76, 169) | 121 (76, 160) | 0.757 |
| WBC (109/L) | 5.24 (3.51, 6.43) | 4.50 (3.72, 5.69) | 0.556 |
| TB (µmol/L) | 93 (48.1, 198.9) | 17.8 (13.5, 24.3) | <0.001a |
| DB (µmol/L) | 83.2 (30.3, 157.4) | 6.7 (4.7, 11.3) | <0.001a |
| ALT (IU/L) | 330 (149, 452) | 42 (22, 97) | <0.001a |
| AST (IU/L) | 394 (208, 557) | 45 (34, 87) | <0.001a |
| AST/ALT | 1.21 (0.98, 1.74) | 1.13 (0.94, 1.65) | 0.694 |
| ALB (g/L) | 34.3 ± 5.4 | 40.1 ± 5.8 | <0.001a |
| GLB (g/L) | 42.7 (35.8, 47) | 35.8 (31.4, 41.3) | 0.001a |
| ALP (IU/L) | 144 (125, 173) | 98 (80, 146) | <0.001a |
| GGT (IU/L) | 128 (63, 225) | 58 (27, 110) | 0.003a |
| PT (s) | 14.7 (13.2, 16.3) | 12.8 (11.9, 13.4) | <0.001a |
| INR | 1.27 (1.12, 1.39) | 1.09 (1.01, 1.13) | <0.001a |
| IgG (g/L) | 30.8 (21.5, 33.2) | 19.3 (16, 24.7) | <0.001a |
|
| |||
| ANA | |||
| <1 : 100 | 4 (12.5%) | 21 (44.7%) | 0.003a |
| ≥1 : 100 | 28 (87.5%) | 26 (55.3%) | |
|
| |||
| AMA | |||
| − | 27 (84.4%) | 43 (97.7%) | 0.322 |
| + | 5 (15.6%) | 1 (2.3%) | |
|
| |||
| LKM | |||
| − | 32 (100%) | 43 (97.7%) | 1.000 |
| + | 0 | 1 (2.3%) | |
|
| |||
| LC-1 | |||
| − | 32 (100%) | 43 (97.7%) | 1.000 |
| + | 0 | 0 | |
| ± | 0 | 1 (2.3%) | |
|
| |||
| SLA | |||
| − | 31 (96.9%) | 41 (93.2%) | 1.000 |
| + | 1 (3.1%) | 3 (6.8%) | |
|
| |||
| ANCA | |||
| − | 14 (77.8%) | 19 (79.2%) | 0.178 |
| + | 2 (11.1%) | 0 | |
| ± | 2 (11.1%) | 5 (20.8%) | |
|
| |||
| Coombs | |||
| − | 6 (42.9%) | 14 (66.7%) | 0.091 |
| + | 8 (57.1%) | 6 (28.5%) | |
| ± | 0 | 1 (4.8%) | |
a P < 0.05. AIH: autoimmune hepatitis; IAIHG: international autoimmune hepatitis group; HGB: haemoglobin; PLT: platelet; WBC: white blood cell; TB: total bilirubin; DB: direct bilirubin; ALT: alanine aminotransferase; AST: aspartate transaminase; ALB: albumin; GLB: globulin; ALP: alkaline phosphatase; GGT: gamma-glutamyl transferase; PT: prothrombin time; INR: international normalized ratio; IgG: immunoglobulin G; ANA: anti-nuclear antibody; AMA: anti-mitochondrial antibody; LKM: liver kidney microsomal; LC: liver cytosol; SLA: soluble liver antigen; ANCA: anti-neutrophil cytoplasmic antibody; Coombs: Coombs test.