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. Author manuscript; available in PMC: 2018 Dec 14.
Published in final edited form as: Cell. 2017 Nov 30;171(7):1611–1624.e24. doi: 10.1016/j.cell.2017.10.044

Figure 5. Intra-tumoral HNSCC heterogeneity recapitulated in nodal metastases.

Figure 5

(A) t-SNE plot of malignant cells (as in Figure 2) from five primary tumors (black) and their matched LNs (red). Malignant cells cluster by tumor rather than by site.

(B) t-SNE plot of non-malignant cells (as in Figure 2) from five primary tumors (black) and their matched LNs (red). Non-malignant cells are consistent across tumors but their representation and expression states vary between sites.

See Figure S6.