Table 3.

Top twenty meta–analysis results of MHC region in POMS cases and controls adjusted for HLA–DRB1*15:01 and HLA–A*02

CHR	BP	SNP	GENE	SUBREGION	OR	p–value
6	32595063	rs28720766	–	Class II	2·16	5·19×10−8a
6	32186245	rs438475	NOTCH4	Class III	0·59	1·51×10−5a
6	32184345	rs404860	NOTCH4	Class III	0·63	2·18×10−5a
6	32184574	rs384247	NOTCH4	Class III	0·64	3·11×10−5a
6	32186193	rs431541	NOTCH4	Class III	0·64	3·14×10−5a
6	32186872	rs2256594	NOTCH4	Class III	0·65	8·95×10−5
6	32629868	rs1049088	HLA–DQB1	Class II	0·67	2·11×10−4
6	32415109	rs3135387	HLA–DRA	Class II	1·55	2·27×10−4
6	31537606	rs2857706	LTA	Class III	1·36	2·74×10−4
6	32411726	rs3129888	HLA–DRA	Class II	1·54	2·88×10−4
6	32679992	rs12527228	–	Class II	1·78	3·03×10−4
6	32372032	rs73400865	BTNL2	Class III	1·55	3·60×10−4
6	31539767	rs2844482	LTA	Class III	1·36	4·02×10−4
6	32592737	rs28421666	–	Class II	1·86	4·80×10−4
6	33054457	rs1042544	HLA–DPB1	Class II	1·26	5·43×10−4
6	32434314	rs12529318	–	–	1·75	5·69×10−4
6	32627700	rs6689	HLA–DQB1	Class II	0·73	6·66×10−4
6	32414420	rs7382085	HLA–DRA	Class II	1·44	9·57×10−4
6	32413317	rs2395182	HLA–DRA	Class II	1·43	9·83×10−4
6	33051683	rs9277411	HLA–DPB1	Class II	1·25	1·15×10−3

CHR=chromosome; BP=base pair; SNP=single nucleotide polymorphism; OR=odds ratio

^aSignificant after multiple comparisons correction