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EL20 suppresses the induction of VT in R176Q mice. Representative simultaneous recordings of surface ECG and intracardiac electrograms after S1–S2 extra stimuli (indicated by arrows) revealed: (A) sinus rhythm in WT mice treated with vehicle, (B) bidirectional and (C) sustained VT in R176Q mice treated with vehicle, (D) sinus rhythm in R176Q mice treated with EL20 (2.5µg/kg). (E) Bar graph summarizing incidence of VT in each set. (*P<0.05, **P<0.01).
