Table 2.

Statistically-significant odds ratios for Z-scores ≤ −1 at age 10 years on the reading (R) assessment only, the mathematics (M) assessment only, or the co-occurrence of low scores on both (B), associated with a concentration in the top quartile of the protein listed on the left, among children whose DAS-II verbal and nonverbal IQs were ≥ 70. This table summarizes Appendix Tables A (individual days) and B (epochs) for these entities. Upper-case regular typeface indicates statistically significantly increased odds ratios, while lower-case italic typeface indicates statistically significantly reduced odds ratios (p < 0.05). Adjustment has been made for birth weight Z-score < −1 and mother’s K-BIT Z-score < −1.

	Protein in highest quartile on: individual day					Two days of epoch
	Day 1	Day 7	Day 14	Day 21	Day 28	Early	Late
Proteins traditionally viewed as inflammation-associated
CRP			M, B	M, B
SAA			M
MPO					M		R, M
IL-1β			B
IL-6					R
IL-6R	R
TNF-α			M
TNF-R1			M
TNF-R2			M	M, B		M
IL-8				M	M		M
RANTES					b		b
ICAM-1	m		B	B			B
VCAM-1
Proteins traditionally viewed as neurotrophic and/or angiogenic
TSH
EPO						B
NT-4		b
BDNF			m		b
bFGF	m
IGF-1
IGFBP-1	M	R		B
VEGF		m
VEGF-R1
VEGF-R2			M
PIGF
Ang-1		b		b
Ang-2