Fig. 4.

Absorption and reduced scattering (${\mu }_{\mathrm{a}}$ and ${\mu }_{\mathrm{s}}^{\prime }$) maps generated using (left) sinusoidal patterns and three-phase demodulation (conventional SFDI), square wave patterns and (middle) three-phase demodulation and (right) MSE approaches, using three-phase-offset square wave patterns at a wavelength of 659 nm. Here we see agreement in ${\mu }_{\mathrm{a}}$ values derived using square waves in the region of interest (ROI, black box) to within 0.5% and 0.3% for three-phase and MSE approaches, respectively. ${\mu }_{\mathrm{s}}^{\prime }$ values show agreement to within 0.2% and 0.5% for three-phase and MSE approaches, respectively. For the entire field of view, the see average ${\mu }_{\mathrm{a}}$ and ${\mu }_{\mathrm{s}}^{\prime }$ values generated using square waves that agree to within 0.78% and 0.45% of conventional SFDI, respectively.