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. 2018 Mar 26;9:558. doi: 10.3389/fimmu.2018.00558

Figure 2.

Figure 2

PA-dPEG24 inhibition of ovalbumin–antiovalbumin immune complex-initated complement activation assayed by complement effectors. (A) PA-dPEG24 inhibition of C5a generation in normal human sera (NHS) stimulated with ovalbumin–antiovalbumin immune complexes (IC). Data are means of (n = 4) independent experiments ± SEM. (B) PA-dPEG24 inhibition of iC3b generation in NHS stimulated with ovalbumin–antiovalbumin IC. Data are means of (n = 4) independent experiments ± SEM. (C) PA-dPEG24 inhibition of SC5b-9 generation in NHS stimulated with ovalbumin–antiovalbumin IC. At 2 mM PA-dPEG24 the measured SC5b-9 was at the lower limit of detection. Data are means of (n = 3) independent experiments ± SEM.