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. 2018 Mar 26;9:274. doi: 10.3389/fphar.2018.00274

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Copyright © 2018 Feng, Huang, Guo, Liang, Xiang, Lei, Shi, Li, Liu, Feng, Ma and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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23BB inhibits the expression of HDAC6 and enhances the acetylation of histone H3. (A) The kidney tissue lysates were subjected to immunoblot analysis with indicated antibodies against HDAC6 and acetylated histone H3. (B) Expressions of HDAC6 and acetylated histone H3 were quantified by densitometry and normalized with β-actin. Data are represented as the means ± SE (n = 6 for each group). ^∗P < 0.05. (C) Immunofluorescence staining of HDAC6 and Lectin in the kidney tissue sections. Lectin was used as a marker of tubular epithelial cells.