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. 2018 Mar 26;9:274. doi: 10.3389/fphar.2018.00274

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Copyright © 2018 Feng, Huang, Guo, Liang, Xiang, Lei, Shi, Li, Liu, Feng, Ma and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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23BB administration suppressed expression level of ER stress proteins. The expression of GRP78, IRE1α, p-eIF2α, ATF4, CHOP, p-JNK, caspase-12, and XBP1, as measured by immunoblot analysis, in kidney tissue sections in each group. The densitometry values of p-JNK were normalized with JNK. The densitometry values of p-eIF2α were normalized with eIF2α. The densitometry values of other proteins were normalized with β-actin. Data are represented as the means ± SE (n = 6 for each group). ^∗P < 0.05.