Table 2.

Multivariable associations between emphysema subtypes and airway disease with expiratory central airway collapse

Variable	Crude OR (95% CI)	P Value	Adjusted OR* (95% CI)	P Value
Substantial centrilobular emphysema†	1.15 (0.90–1.48)	0.26	1.05 (0.82–1.35)	0.70
Substantial paraseptal emphysema	0.86 (0.62–1.20)	0.38	1.11 (0.83–1.48)	0.49
Definite bronchial wall thickening	1.17 (0.91–1.51)	0.21	1.11 (0.89–1.40)	0.35
Paratracheal paraseptal emphysema	1.48 (1.07–2.05)	0.02	1.53 (1.18–1.98)	0.001

Definition of abbreviations: CI = confidence interval; OR = odds ratio.

^*Adjusted for age, sex, race, body mass index, pack-years smoking history, current smoking status, and forced expiratory volume in 1 second, with Global Initiative for Obstructive Lung Disease stage as strata condition.

^†Substantial centrilobular emphysema = presence of any of moderate, confluent, or advanced destructive centrilobular emphysema.