Table 1. Characteristics of Various Nanoparticle-Based Imaging Modalities.
imaging modality | imaging probe | spatial resolution | molecular sensitivity | maximum penetration depth |
---|---|---|---|---|
magnetic resonance imaging (MRI) | para-/superpara-/ferromagnetic nanoparticles (Gd, Fe, Mn, etc.) | ∼100 μm | μM–mM | no limit |
computed tomography (CT) | nanoparticles of high-Z elements (Ba, I, Au, Ta, etc.) | ∼100 μm | ∼1 mM | no limit |
anti-Stokes shift-based optical imaging | doped quantum dots, upconverting nanoparticles | <1 μm | <1 μM | <1 mm |