Table 1. Textural Properties of MOFs before and after Drug Adsorption Processa.
| before
encapsulation |
after
drug encapsulation |
||||||
|---|---|---|---|---|---|---|---|
| MOF | drug | Vp (cm3·g–1) | SBET (m2·g–1) | Vp (cm3·g–1) | SBET (m2·g–1) | drug wt % (mol·mol–1) | drug occupancy volume (A3·molecule–1) |
| MIL-100 | IBU | 1.42 | 1940 | 0.34 | 509 | 30.6 ± 0.9 (1.0) | 1078 (474)b |
| AAS | 0.57 | 1072 | 24.8 ± 0.8 (1.0) | 763 (336)b | |||
| UiO-66 | IBU | 0.64 | 1349 | 0.12 | 383 | 35.5 ± 3.2 (3.7) | 347 |
| AAS | 0.32 | 724 | 25.5 ± 3.7 (3.0) | 199 | |||
| MIL-127 | IBU | 0.47 | 1304 | 0.09 | 105 | 13.6 ± 0.7 (0.5) | 1272 (250)b |
| AAS | 0.37 | 836 | 4.4 ± 0.6 (0.2) | 1224 (241)b | |||
a
Total drug loading (wt % and mol·mol–1) and estimated occupancy volume of a single drug molecule (A3·molecule–1).
b
Estimated considering a selective occupation of the porosity.