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. 2018 Apr 2;19:77. doi: 10.1186/s12882-018-0875-8

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Kaplan-Meier survival curve of admitted-discharged patients affected with MALA (admission, time 0 – 25 days). Discharged patients are marked as censored. During the follow-up (mean 27.2 months), none of the surviving patients experienced new episodes of lactic acidosis after discontinuing the drug. Two patients died at follow-up for reasons other than lactic acidosis