Table 8.
Treatment effect of dialysate to serum sodium alignment on volume-related and hemodynamic parameters in those patients part to this quality initiative (as-treated cohort; N = 137) and the propensity score matched control cohort (N = 137)
Parameter | Study Regimen | Baseline | Follow-up | Difference (95% CI) | Treatment effect (95% CI) |
---|---|---|---|---|---|
Pre HD SBP [mmHg] | aligned | 143.42+/−21.27 | 143.06+/−21.2 | −0.36 (−5.41 to 4.69) | 1.68 (−0.87 to 4.23) |
unaligned | 146.94+/−20.88 | 144.9+/−22 | −2.04 (−7.15 to 3.07) | ||
Post HD SBP [mmHg] | aligned | 132.8+/−16.83 | 133.36+/−17.68 | 0.56 (−3.55 to 4.67) | 1.43 (−0.86 to 3.72) |
unaligned | 137.57+/−19.27 | 136.7+/−19.7 | −0.87 (−5.5 to 3.76) | ||
Pre HD DBP [mmHg] | aligned | 73.23+/−13.03 | 72.99+/−12.65 | −0.24 (−3.3 to 2.81) | 0.43 (−0.94 to 1.8) |
unaligned | 75.9+/−12.16 | 75.2+/−12.1 | −0.67 (−3.56 to 2.21) | ||
Post HD DBP [mmHg] | aligned | 68.14+/−9.59 | 68.23+/−10.13 | 0.09 (−2.26 to 2.44) | 0.34 (−0.91 to 1.58) |
unaligned | 70.97+/−10.62 | 70.7+/−10.3 | −0.25 (−2.74 to 2.24) | ||
Pre HD PP [mmHg] | aligned | 70.19+/−15.3 | 70.07+/−15.6 | −0.12 (−3.79 to 3.56) | 1.25 (−0.4 to 2.9) |
unaligned | 71.05+/−15.24 | 69.7+/−15.9 | −1.37 (−5.07 to 2.34) | ||
Post HD PP [mmHg] | aligned | 64.66+/−13.4 | 65.13+/−13.7 | 0.47 (−2.75 to 3.69) | 1.09 (−0.38 to 2.57) |
unaligned | 66.59+/−13.91 | 66+/−14.4 | −0.62 (−4 to 2.75) | ||
Pre HD MAP [mmHg] | aligned | 96.63+/−14.56 | 96.35+/−14.23 | −0.28 (−3.71 to 3.14) | 0.85 (−0.83 to 2.52) |
unaligned | 99.58+/−13.86 | 98.5+/−14.3 | −1.13 (−4.47 to 2.22) | ||
Post HD MAP [mmHg] | aligned | 89.7+/−10.76 | 89.94+/−11.44 | 0.25 (−2.4 to 2.89) | 0.7 (−0.82 to 2.22) |
unaligned | 93.17+/−12.49 | 92.7+/−12.4 | −0.45 (−3.41 to 2.51) | ||
Intra HD SBP change [mmHg] | aligned | −10.61+/−13.72 | −9.7+/−14.67 | 0.92 (−2.46 to 4.3) | −0.25 (−2.65 to 2.14) |
unaligned | −9.38+/−14.23 | −8.2+/−14.7 | 1.17 (−2.27 to 4.61) | ||
Intra HD DBP change [mmHg] | aligned | −5.09+/−6.8 | −4.76+/−7.3 | 0.33 (−1.34 to 2.01) | −0.09 (−1.24 to 1.05) |
unaligned | −4.92+/−6.98 | −4.5+/−7 | 0.43 (−1.23 to 2.09) |