Table 1.
Baseline Demographics
| All patients n = 62 | GH deficient n = 29 | Non-GH deficient n = 18 | |
|---|---|---|---|
| Age (median, IQR) | 43 (21.8) | 46 (17) | 39 (18) p = 0.216 |
| Gender | M: n = 29 | M: n = 15 | M: n = 7 |
| F: n = 33 | F: n = 14 | F: n = 11 | |
| Weight (median, IQR) | 78.1 kg (32.3) | 83 kg (34.0) | 74.2 kg (23.6) p = 0.220 |
| #months to endo referral (median, IQR) | 20 (16) | 24 (13) | 15 (20) p = 0.317 |
| TBI Severity | Mild n = 48 | Mild n = 22 | Mild n = 17 |
| Mod n = 6 | Mod n = 1 | Mod n = 1 | |
| Severe n = 8 | Severe n = 6 | ||
| Documented Sport Concussion | n = 15 | n = 7 | n = 5 |
| Hockey n = 4 | Hockey n = 3 | Basketball n = 1 | |
| Cycling n = 2 | Cycling n = 2 | Dirt biking n = 1 | |
| Basketball n = 2 | Basketball n = 1 | Football n = 1 | |
| Soccer n = 2 | Football n = 1 | Equestrian n = 1 | |
| Football n = 2 | Soccer n = 1 | ||
| Dirt biking n = 1 | |||
| Wrestling n = 1 | |||
| Equestrian n = 1 | |||
| Documented pituitary deficits | n = 4 | n = 2 | n = 1 |
| n = 1 secondary hypothyroidism | n = 1 secondary hypothyroidism | n = 1 secondary hypogonadism and hypothyroidism | |
| n = 2 secondary hypogonadism | n = 1 secondary hypogonadism | ||
| n = 1 secondary hypothyroidism and secondary hypogonadism | |||
| IGF-1 Z score (median, IQR) | −0.193 (2.07) | −0.214 (1.52) | −0.060 (1.24) p = 0.979 |
| Peak GH during stim test (median, IQR) | 3.8 μg/L (6.9) | 1.3 μg/L (2.6) | 9.7 μg/L (4.3) p = < 0.001 |