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. 2018 Apr 2;13:65. doi: 10.1186/s13018-018-0769-2

Table 4.

Associations between FTO polymorphism and BMI when stratified by gender and OA status

Groups compared CC vs. other combined TT vs. other combined C allele vs. T allele All genotype
P value OR 95% CI P value OR 95% CI P value OR 95% CI P value
Total overweight and obese cases (n = 892) vs. controls (n = 842) 0.867 0.984 0.811–1.19 0.901 1.012 0.778–1.33 0.856 0.987 0.861–1.13 0.983
Overweight and obese cases (n = 423) vs. controls (n = 405) in females 0.835 0.971 0.734–1.28 0.738 1.07 0.725–1.57 0.750 0.968 0.794–1.18 0.940
Overweight and obese cases (n = 469) vs. controls (n = 437) in males 0.973 0.995 0.762–1.30 0.882 0.972 0.670–1.41 0.959 1.00 0.831–1.22 0.985
Overweight and obese cases (n = 482) vs. controls (n = 408) in OA cases 0.818 1.03 0.786–1.36 0.966 1.01 0.692–1.47 0.888 1.01 0.837–1.23 0.967
Overweight and obese cases (n = 410) vs. controls (n = 434) in OA controls 0.707 0.948 0.720–1.25 0.886 1.03 0.701–1.51 0.731 0.966 0.793–1.18 0.931