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Interactions between Papi and the RGRRR motif of Piwi are conserved among Drosophila species. (A) Sequence alignment of Piwi among Drosophila species. (B) Superimposition of the eTud domain structures of Papi, Tud, Tdrd1, and SND1. The protruding loop is circled. Color coding: Papi-eTud, wheat; Tud-eTud, orange; Tdrd1-11th eTud, pink; SND1-eTud, blue. The PDB ID code of each structure is given in Supporting Information. (C) Close-up view of the protruding loop circled in B.
