Fig. 6.

Ketamine and scopolamine, but not GLYX-13 or Ro 25-6981, increase excitability in a neural population. In extracellular recordings, bath application of ketamine (A; *P < 0.05, n = 6) and scopolamine (B; *P < 0.05, n = 10) significantly increases pyramidal cell excitability, while there is no effect with GLYX-13 (C, n = 12) or Ro 25-6981 (D, n = 7). n.s., not significant. In control experiments, switching between two containers of aCSF had no effect on excitability (E, n = 37). (Scale bars: 1 mV and 10 ms.) All values are mean ± SEM.