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. 2001 Sep 25;98(20):11725–11730. doi: 10.1073/pnas.211132798

Figure 4.

Figure 4

Effects of GluR2 C-terminal peptide on NMDA receptor-mediated EPSC and pairing-induced LTP. (A) Effect of −SVKI peptide on NMDA receptor-mediated EPSC. As a control, −SGKA peptide was used. (Insets) The average traces of 20 traces from one example experiment measured at 8 (designated 1) and 70 min (designated 2) after whole-cell recording. The average EPSC at 30 min after whole cell (or right before pairing) was 110 ± 1% compared with the initial 2-min average EPSC. (Scale bar, 25 pA and 50 ms.) (B) Effect of −SVKI peptide on NMDA receptor-dependent LTP induced by pairing. Arrow indicates the time of pairing. (Scale bar, 160 pA and 15 ms.) Gray bar indicates the period of postsynaptic application of peptides. * indicates stimulus artifact, which is cut off.