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. 2018 Apr 2;18:362. doi: 10.1186/s12885-018-4235-7

Table 13.

VOCs discriminating the headspace of lung cancer cell lines and control cell lines. Analysis of abundances of VOCS in the headspace of lung cancer, breast cancer and normal lung cell lines using GCMS-SPME. A p-value < 0.05 has been considered statistically significant

Compounds P-values
A549/Calu3 A549/MCF7 A549/WI38VA13 Calu3/MCF7 Calu3/WI38VA13
Decane 0.326 (↑) 0.154 (↑) 1.04E-4 (↑) 0.127 (↓) 0.016 (↑)
Propylbenzene 0.507 (↑) 0.533 (↑) 0.104 (↓) 0.988 (↓) 0.071 (↓)
Dodecane 1.67E-6 (↓) 2.23E-5 (↓) - 0.011 (↑) 1.67E-6 (↑)
Decanal 0.001 (↑) 0.001 (↑) 0.001 (↑) - -
Nonanal 0.002 (↑) 0.002 (↑) 1.17E-4 (↓) - 2.21E-4 (↓)
3, 4-Dimethylheptane - 2.75E-4 (↓) - 2.75E-4 (↓) -
2, 4-DimethylUndecane - - 0.017 (↓) 0.017 (↓) -
2-Ethyldodecanol 3.88E-5 (↓) - - 3.88E-5 (↑) 3.88E-5 (↑)
2-Ethylhexanol 3.53E-5 (↓) - 2.47E-7 (↓) 3.53E-5 (↑) 9.40E-5 (↑)
Heneicosane 0.334 (↓) 0.002 (↑) 0.002 (↑) 3.40E-4 (↑) 3.40E-4 (↑)

The (↑) and (↓) shows the trend of abundances increases and decreases in lung cancer cell line samples respectively