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. 2018 Apr 2;18:116. doi: 10.1186/s12906-018-2183-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Açaí decreased angiogenesis markers immunodistribution in breast cancer. The immunoreactivity of VEGF and VEGFR-2 were detected predominantly around the glands (*) in control group (a, b). Treated breast cancer lesions (d, e) exhibited a significant decrease in reaction intensity (*). MMP-9 immunoreactivity was the same (*) in the control (c) and the açaí (f). Histomorphometry evaluations of VEGF, VEGFR-2 and MMP-9. ELISA analysis (h) indicated that the VEGF levels were higher in the control than in the açaí