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. 2018 Apr 2;13:7. doi: 10.1186/s12263-018-0597-3

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — pQTL analysis of SNPs associated with the change in circulating ANGPTL3 during weight loss. Manhattan plot of pQTL analysis of SNPs associated with the change in circulating ANGPTL3 during weight loss. Each SNP is indicated by a black or a gray dot. They are arranged by chromosomal location (x-axis). The y-axis illustrates the level of statistical significance measured by the negative log of the corresponding p value for each SNP. The blue line represents suggestive association (p < 1 × 10⁻⁵)