Table 1.
Strengths and weakness of measuring muscle mass by dual energy X‐ray absorptiometry
| Strengths | Weaknesses |
|---|---|
| Non‐invasive with small doses of radiation (<1 μSv for whole‐body scans).41 | Projectional technique, individual muscles cannot be assessed separately. |
| Relatively cheap, compared with CT scan or MRI. | Not portable, which may preclude its use in large‐scale epidemiological studies and studies in the home setting. |
| Rapid | Availability is limited in some care settings. |
| Allows measurement of three body compartments. | Body thickness and abnormalities in hydration status (e.g. water retention, heart, kidney, or liver failure) can affect muscle mass measure.42 |
| Low precision errors | Very tall and very obese people cannot be measured. |
| Cannot quantify fatty infiltration of muscle. It is a bias in the diagnosis of sarcopenia obesity. | |
| Does not measure skeletal muscle mass in non‐limb regions of the body (e.g. trunk). | |
| Several devices and several software packages and software versions resulting in different results. |
CT, computed tomography; MRI, magnetic resonance imaging.