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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Thromb Haemost. 2018 Feb 16;118(3):502–513. doi: 10.1055/s-0038-1627453

Fig. 2.

Fig. 2

Effect of TFPI-α inhibition on kinetics of platelet-dependent fibrin formation under flow. Platelet thrombi were generated by perfusion of DiOC6-labeled human blood over microspots with collagen and indicated amounts of TF, as for Fig. 1. Platelet thrombi were superfused with recalcified normal plasma containing AF647 fibrinogen. Shown are representative confocal fluorescence images (no TF, time points indicated) after perfusion with vehicle-treated plasma (A) or TFPI-α-inhibited plasma (B). Bars = 25 μm. Time traces of fibrin formation (C) and platelet adhesion (D) (fluorescence image analysis) at platelet thrombi for microspots with 0, 2 and 10 pM TF (n = 3).